The largest study ever to examine the association of dietary fat and risk of prostate cancer found that it is good for the heart can not be good for the prostate.The mechanisms underlying the impact of omega-3 on the risk of high-grade prostate cancer are unknown. ?Besides inflammation, omega-3 affect other biological processes. It may be that these mechanisms play a greater role in the development of some prostate cancers,? said Brasky.?
Women who have been treated for breast cancer may choose to get pregnant and have children without fear that pregnancy could put them at higher risk of dying from their cancer, according to a new study.
The researchers undertook the study because chronic inflammation is known to increase the risk of several cancers, and omega-3 fatty acids are found primarily in fish and fish oil supplements have anti-inflammatory effects. In contrast, other fats such as omega-6 fatty acids in vegetable oils and trans fats in foods quickly, can promote inflammation. ?We wanted to test the hypothesis that the concentrations of these fats in the blood are associated with risk of prostate cancer,? said Brasky. ?In particular, we thought it would reduce the omega-3 and omega-6 and trans fatty acids increase the risk of prostate cancer
?Overall, the benefits of fish consumption to prevent heart disease outweigh the harm associated with risk of prostate cancer,? said Brasky. ?What this study demonstrates the complexity of nutrition and its impact on disease risk, and that we should study these associations rigorously rather than make assumptions,? said Brasky.
The study was based on data from the Prostate Cancer Prevention Trial, a randomized clinical trial at the national level that has tested the effectiveness of the drug finasteride to prevent prostate cancer. While the process has involved nearly 19,000 men aged 55 and over, the data in this analysis were a subset of more than 3,000 study participants, half of whom developed prostate cancer during the study and half not. The study was unique in that prostate biopsy was used to confirm the presence or absence of prostate cancer in all study participants.
There is currently no official recommended daily intake of omega-3 for adults or children, although many nutrition experts and doctors recommend 450 mg of omega-3 DHA per day as part of a healthy diet.
So, on the basis of these results, should men concerned about heart disease to avoid fish oil supplements or grilled salmon, in the interest of reducing their risk of aggressive prostate cancer? Brasky and colleagues do not think so.
In contrast, the study also found that men with more blood relations, trans fatty acids that are linked to heart disease and inflammation, and abundant in processed foods containing partially hydrogenated vegetable oils had a 50 % risk high quality prostate cancer. Moreover, none of these fats has been associated with the risk of low risk of prostate cancer.
The researchers also found that omega-6 fatty acids in vegetable oils and are linked to inflammation and heart disease are not associated with risk of prostate cancer.
Source: http://www.exercise24.org/?p=212
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